Local Shear Stress and Brachial Artery Flow-Mediated Dilation

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Local Shear Stress and Brachial Artery Flow–Mediated Dilation

Endothelium-dependent flow-mediated dilation is a homeostatic response to short-term increases in local shear stress. Flow-mediated dilation of the brachial artery in response to postischemic reactive hyperemia is impaired in patients with cardiovascular disease risk factors and may reflect local endothelial dysfunction in the brachial artery. However, previous studies have largely neglected th...

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Local shear stress and brachial artery flow-mediated dilation: the Framingham Heart Study.

Endothelium-dependent flow-mediated dilation is a homeostatic response to short-term increases in local shear stress. Flow-mediated dilation of the brachial artery in response to postischemic reactive hyperemia is impaired in patients with cardiovascular disease risk factors and may reflect local endothelial dysfunction in the brachial artery. However, previous studies have largely neglected th...

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Flow-Mediated Dilation: Just a Marker of Local Shear Stress?

Local Shear Stress? To the Editor: We read with interest the article by Mitchell et al1 and agree that flow-mediated dilation (FMD%) response may be partially explained by shear stress (diastolic shear stress [DSS]) or flow changes.2 However, this does not necessarily mean that risk factors do not influence the vascular response. Indeed, Megnien et al3 showed that shear stress reduction provoke...

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Flow-mediated dilation: just a marker of local shear stress?

Local Shear Stress? To the Editor: We read with interest the article by Mitchell et al1 and agree that flow-mediated dilation (FMD%) response may be partially explained by shear stress (diastolic shear stress [DSS]) or flow changes.2 However, this does not necessarily mean that risk factors do not influence the vascular response. Indeed, Megnien et al3 showed that shear stress reduction provoke...

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Shear stress and flow-mediated dilation.

In this edition of Hypertension, the Framingham Heart Study group reports on the relationship between diastolic shear stress and brachial artery flow mediated dilation (FMD) in 2045 participants of the Framingham Offspring group.1 Clinical correlates and heritability of FMD in the participants have been published previously.2 The new report1 challenges conventional concepts on endothelial funct...

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ژورنال

عنوان ژورنال: Hypertension

سال: 2004

ISSN: 0194-911X,1524-4563

DOI: 10.1161/01.hyp.0000137305.77635.68